Drug intelligence / Profile preview

Shingrix + Arexvy

Development stage
Unknown
Lead developer
GSK
Modality
Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
Administration
Intramuscular
01

Overview

Shingrix + Arexvy is a co-administration regimen of two vaccines developed by GSK. Shingrix is a recombinant subunit vaccine containing varicella-zoster virus glycoprotein E and the AS01B adjuvant, approved for the prevention of shingles. Arexvy is a recombinant subunit vaccine containing the RSV pre-fusion F protein (RSVPreF3) and the AS01E adjuvant, approved for the prevention of respiratory syncytial virus (RSV) infection. The co-administration of these two vaccines is being studied in Phase 3 clinical trials (such as NCT05966090) to evaluate safety and immunogenicity in adults aged 50 and older, aiming to streamline adult immunization schedules and reduce healthcare visits.

Other names
Recombinant Zoster VaccineRZVRSVPreF3RSVPreF-3RSVPreF 3Respiratory Syncytial Virus Vaccine, Recombinant, Adjuvanted
02

Targets

RSV F (Respiratory syncytial virus fusion protein)gE (VZV glycoprotein E)

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