Drug intelligence / Profile preview

Shinjimun

Development stage
Unknown
Lead developer
Catalyst Ryukyu
Modality
Small Molecules
Administration
Oral
01

Overview

Shinjimun is a nutraceutical and botanical drug candidate developed by Catalyst Ryukyu Co., Ltd., derived from the Okinawan medicinal herb *Peucedanum japonicum*, commonly known as Chomeiso or Long-life herb. The product is designed to address metabolic disorders, including obesity, diabetes, and metabolic syndrome, by leveraging the bioactive properties of the plant's constituents, such as coumarins (e.g., isosamidin) and polyphenols. Shinjimun functions primarily as a dual agonist of peroxisome proliferator-activated receptors alpha (PPAR-alpha) and gamma (PPAR-gamma), which play critical roles in regulating lipid metabolism and insulin sensitivity. Catalyst Ryukyu, based in Okinawa, Japan, focuses on the Shinjimun (medicine/soul food) philosophy to develop functional foods and pharmaceutical candidates from local biodiversity. While currently available as a dietary supplement, the extract is also being explored under the development code CR-001 for potential pharmaceutical applications.

Brand names
Shinjimun
Other names
Chomeiso extractPeucedanum japonicum extract
02

Targets

PPARG (Peroxisome proliferator-activated receptor gamma)PPARA (Peroxisome proliferator-activated receptor alpha)

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