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Shinjimun is a nutraceutical and botanical drug candidate developed by Catalyst Ryukyu Co., Ltd., derived from the Okinawan medicinal herb *Peucedanum japonicum*, commonly known as Chomeiso or Long-life herb. The product is designed to address metabolic disorders, including obesity, diabetes, and metabolic syndrome, by leveraging the bioactive properties of the plant's constituents, such as coumarins (e.g., isosamidin) and polyphenols. Shinjimun functions primarily as a dual agonist of peroxisome proliferator-activated receptors alpha (PPAR-alpha) and gamma (PPAR-gamma), which play critical roles in regulating lipid metabolism and insulin sensitivity. Catalyst Ryukyu, based in Okinawa, Japan, focuses on the Shinjimun (medicine/soul food) philosophy to develop functional foods and pharmaceutical candidates from local biodiversity. While currently available as a dietary supplement, the extract is also being explored under the development code CR-001 for potential pharmaceutical applications.
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