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Shiwei Longdanhua
- Development stage
- Unknown
- Lead developer
- Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Shiwei Longdanhua is a Traditional Tibetan Medicine (TTM) formulation used primarily for the treatment of respiratory conditions such as acute tracheobronchitis and chronic bronchitis. The formula consists of ten botanical ingredients, with *Gentiana algida* (Longdanhua) serving as the principal component. It is traditionally indicated for clearing heat, resolving phlegm, and relieving cough, specifically targeting the 'phlegm-heat obstructing the lung' syndrome. Clinical evaluations, including those sponsored by institutions like The Second Affiliated Hospital of Tianjin University of Chinese Medicine, focus on its efficacy in reducing cough severity and sputum production while maintaining a favorable safety profile. The therapeutic effects are attributed to the synergistic anti-inflammatory, antitussive, and expectorant properties of its constituent herbs, which include *Terminalia chebula* and *Adhatoda vasica*.
- Brand names
- Shiwei Longdanhua capsule
- Other names
- Shiwei Longdanhua JiaonangShiwei Longdanhua formulaShiwei Longdanhua granules
02
Targets
NeuraminidaseMisfolded SOD1
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