Drug intelligence / Profile preview

SHJ002

Development stage
Phase 2
Lead developer
Sunhawk Vision Biotech
Modality
Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Small Molecules, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
Administration
Ophthalmic
01

Overview

SHJ002 is an antisense oligonucleotide therapy formulated as a sterile ophthalmic solution (eye drops) designed to neutralize microRNA-328. By inhibiting microRNA-328, which has been implicated as a risk factor for myopia development, the drug acts through gene silencing and microRNA inhibition mechanisms. It is being developed primarily for the treatment of myopia in children and adolescents, dry eye disease (keratoconjunctivitis sicca), and corneal disorders such as corneal erosion in patients with Sjogren's syndrome. The developer and manufacturer is Sunhawk Vision Biotech. Clinical trials have demonstrated that SHJ002 is generally safe and well-tolerated when administered as eye drops[2][3][4][5][6][7].

Other names
microRNA-328 antisense oligonucleotidemicroRNA328 antisense oligonucleotidemicroRNA 328 antisense oligonucleotidemiRNA-328 antisense oligonucleotidemiRNA328 antisense oligonucleotidemiRNA 328 antisense oligonucleotideAnti-myopia eyedrop

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