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Shou Zu Ning No. 1 Formula
- Development stage
- Unknown
- Lead developer
- Longhua Hospital Shanghai University of Traditional Chinese Medicine
- Administration
- Topical
01
Overview
Shou Zu Ning No. 1 Formula is a Traditional Chinese Medicine (TCM) herbal preparation primarily utilized for the prevention and treatment of hand-foot syndrome (HFS), also known as palmar-plantar erythrodysesthesia (PPE). This condition is a common dermatological toxicity associated with chemotherapy agents such as capecitabine and targeted therapies like sorafenib or sunitinib. The formula is typically administered as a topical soak or wash and is designed to alleviate symptoms including erythema, edema, pain, and desquamation of the extremities. Developed and extensively studied at institutions like Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine, the formula acts by clearing heat, detoxifying, and promoting local blood circulation to mitigate the inflammatory response in the skin tissues of the hands and feet.
- Brand names
- Shou Zu Ning No. 1 Formula
- Other names
- 手足宁1号方Shou Zu Ning 1 Hao Fang
02
Targets
TNFA (Tumor necrosis factor alpha (soluble))PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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