Drug intelligence / Profile preview

Shouhui Tongbian Capsule

Development stage
Phase 4
Lead developer
Lunan Houpu Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Shouhui Tongbian Capsule (developed under the clinical name Yunchang Capsule or YunChang Collocystis) is a traditional Chinese medicine (TCM) proprietary product developed by Lunan Hope Pharmaceutical for the treatment of functional constipation, particularly cases characterized by deficiency of both qi and yin complicated by internal accumulation of toxic pathogens. The formulation consists of eight herbal ingredients: Ginseng, Aloe, Polygonum multiflorum (He Shou Wu), Donkey-hide gelatin (Ejiao), Goji berry, Cassia seed, Atractylodes macrocephala, and Immature Bitter Orange. It works by promoting intestinal movement, shortening defecation time, increasing fecal water content, and regulating the gut microbiota and bile acid metabolism.

Brand names
Shouhui Tongbian CapsuleShouhui Tongbian Capsules首荟通便胶囊
Other names
YunChang CollocystisYunchang CapsuleYunchang Capsules运肠胶囊
02

Targets

AQP3 (Aquaporin-3 channel protein)AHR (Aryl hydrocarbon receptor)CDK2 (Cyclin-dependent kinase 2)

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