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shouwu glycoside lipid-lowering capsule
- Development stage
- Unknown
- Lead developer
- Chengdu High-tech Zone Yaogong Pharmaceutical Biotechnology Research Institute
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Shouwu glycoside lipid-lowering capsule is a traditional Chinese medicine (TCM) therapeutic candidate developed by the Chengdu High-tech Zone Yaogong Pharmaceutical Biotechnology Research Institute for the treatment of hyperlipidemia. The formulation is primarily composed of glycosides extracted from *Polygonum multiflorum* (He Shou Wu), a plant traditionally used in Chinese medicine for its purported ability to regulate blood lipids and support cardiovascular health. The drug is designed to lower serum cholesterol and triglyceride levels, potentially through the modulation of lipid metabolism pathways. It has undergone Phase 1 clinical evaluation in China to assess its safety, tolerability, and pharmacokinetic profile in healthy adult volunteers.
- Brand names
- Shouwugan Jiangzhi
- Other names
- 首乌苷降脂胶囊Shouwu Gan Jiangzhi JiaonangShouwu glycoside lipid-lowering capsule
02
Targets
HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)
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