shox2 morpholino

shox2 morpholino is a synthetic antisense oligonucleotide used as a research tool to knock down the expression of the Short stature homeobox 2 (shox2) gene. Morpholinos function by binding to complementary sequences of RNA, typically blocking the translation initiation complex or interfering with pre-mRNA splicing. In developmental biology, particularly in zebrafish models, shox2 morpholinos are employed to investigate the gene's role in the development of the heart, brain, and limbs. Research has indicated that shox2 deficiency leads to altered expression of fibroblast growth factor receptor 3 (fgfr3) and natriuretic peptides, providing insights into conditions like short stature and cardiac stress.

Other names

shox2 antisense morpholinoshox-2 antisense morpholinoshox 2 antisense morpholinoshox2 morpholino oligonucleotideshox-2 morpholino oligonucleotideshox 2 morpholino oligonucleotide