Drug intelligence / Profile preview

SHR-3167 + insulin glargine

Development stage
Unknown
Lead developer
Hengrui Pharmaceutical
Modality
Peptides
Administration
Subcutaneous
01

Overview

SHR-3167 + insulin glargine refers to the clinical evaluation or combination of SHR-3167, an investigational long-acting basal insulin analog, and insulin glargine, a standard-of-care basal insulin. Developed by Jiangsu Hengrui Pharmaceuticals, SHR-3167 is designed for the treatment of type 2 diabetes mellitus. It acts as an agonist of the insulin receptor, mimicking the physiological role of endogenous insulin to regulate glucose metabolism by promoting peripheral glucose uptake and inhibiting hepatic glucose production. Phase I clinical trials have focused on comparing the pharmacokinetics, pharmacodynamics, and safety profile of SHR-3167 against insulin glargine (U100) in both healthy volunteers and patients with type 2 diabetes to establish its potential as a long-acting basal therapy.

Other names
SHR-3167 injection + glargine insulin
02

Targets

INSR (Insulin receptor)IGF-1R (Insulin-like growth factor 1 receptor)

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