Drug intelligence / Profile preview

Shu Jin San

Development stage
Unknown
Lead developer
Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Modality
Small Molecules
Administration
Oral
01

Overview

Shu Jin San (specifically Lyu's Shu Jin San in the provided context) is a Traditional Chinese Medicine (TCM) herbal formulation used for the treatment of musculoskeletal disorders, particularly rheumatoid arthritis (RA) characterized by cold-dampness syndrome. Developed and utilized by the Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, it is often administered as an adjunctive therapy alongside conventional disease-modifying antirheumatic drugs (DMARDs) like methotrexate. The formula aims to alleviate joint pain, reduce swelling, and improve mobility by relaxing the tendons and expelling cold and dampness according to TCM principles. As a complex herbal mixture, it likely exerts its effects through a multi-target approach involving the modulation of inflammatory cytokines and immune pathways.

Other names
Lyu's Shu Jin San吕氏舒筋散
02

Targets

TP53 (Cellular Tumor Antigen p53 R175H)MMP2 (Matrix metalloproteinase-2)CCNB1 (Cyclin B1)

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