Drug intelligence / Profile preview

shuanghuanglian inhalation solution

Development stage
Preclinical
Lead developer
Beijing Yingkerei Pharmaceutical Technology
Administration
Inhalation
01

Overview

Shuanghuanglian Inhalation Solution is a traditional Chinese medicine (TCM) candidate being developed by Beijing Yingkerei Pharmaceutical Technology for the treatment of respiratory infections. The formulation is a nebulized solution of the classic Shuanghuanglian formula, which is composed of extracts from *Lonicera japonica* (Japanese Honeysuckle), *Scutellaria baicalensis* (Baikal Skullcap), and *Forsythia suspensa* (Weeping Forsythia). This combination is traditionally used for its broad-spectrum antiviral, antibacterial, and anti-inflammatory properties. By delivering the medication via inhalation, the treatment aims to achieve high local concentrations in the respiratory tract, potentially improving efficacy and safety for conditions such as acute bronchitis and upper respiratory tract infections. It is currently in the preclinical stage of development.

Other names
吸入用双黄连溶液Shuanghuanglian Inhalation SolutionShuanghuanglian-Beijing Yingkerei Pharmaceutical Technology-traditional Chinese medicine-inhalation (nebulization)-respiratory infections
02

Targets

BCL-2 (BCL-2 family)Mpro (3C-like proteinase of SARS-CoV-2)EGFR T790M (Epidermal growth factor receptor T790M mutant)IL-6 (Interleukin 6)PLpro (Papain-like protease)

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