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Shuanghuangsanjie Formula is a Traditional Chinese Medicine (TCM) herbal preparation developed by the Yue Yang Hospital of Integrated Traditional Chinese and Western Medicine, which is affiliated with the Shanghai University of Traditional Chinese Medicine. The formula is primarily investigated for its therapeutic potential in managing early pulmonary ground-glass nodules (GGNs). Based on TCM principles, it is designed to clear heat, resolve phlegm, and dissipate nodules (Sanjie). In clinical research, it is frequently evaluated in combination with Tianwuxiaoliu Tablets to assess its efficacy in stabilizing or reducing nodule size and its impact on the psychological well-being of patients who do not yet have surgical indications or have declined surgery.
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