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Shuangpi Zhuoyu prescription is a topical traditional Chinese medicine (TCM) formula developed by Xiyuan Hospital of the China Academy of Chinese Medical Sciences. It is specifically formulated to treat rosacea, particularly the "toxin heat stasis syndrome" pattern according to TCM diagnostic criteria. The prescription is designed to clear heat, detoxify, and resolve blood stasis in the skin. In clinical studies (such as ChiCTR2200064018), it is evaluated as a topical treatment compared against standard metronidazole gel to assess its impact on clinical lesion scores, patient quality of life, and inflammatory biomarkers. As a multi-component herbal therapy, it likely exerts its effects through broad anti-inflammatory and microcirculatory modulation.
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