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Shufeng Zhitong Capsule
- Development stage
- Phase 3
- Lead developer
- Beijing Boshili Pharmaceutical Technology
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Shufeng Zhitong Capsule is a Traditional Chinese Medicine (TCM) formulation currently in Phase III clinical development for the preventive treatment of migraine. Developed by Beijing Boshili Pharmaceutical Technology, the drug is specifically indicated for patients presenting with the "cold coagulation and blood stasis with wind" syndrome (寒凝血瘀证). The capsule contains a blend of herbal extracts designed to dispel wind, dissipate cold, and resolve blood stasis, thereby reducing the frequency and severity of migraine attacks. It is being evaluated in a multicenter, randomized, double-blind, placebo-controlled trial (e.g., CTR20254404) to establish its efficacy and safety as a prophylactic therapy.
- Brand names
- Shufeng Zhitong Capsule
- Other names
- 疏风止痛胶囊
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)DRD2 (Dopamine D2 Receptor)IL1B (Interleukin-1 beta)IL-6 (Interleukin 6)MEKCaV (Voltage-gated calcium channel protein complex)
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