Drug intelligence / Profile preview

Shufeng Zhitong Capsule

Development stage
Unknown
Lead developer
Beijing Boshili Pharmaceutical Technology
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Shufeng Zhitong Capsule is a Traditional Chinese Medicine (TCM) formulation currently in Phase III clinical development for the preventive treatment of migraine. Developed by Beijing Boshili Pharmaceutical Technology, the drug is specifically indicated for patients presenting with the "cold coagulation and blood stasis with wind" syndrome (寒凝血瘀证). The capsule contains a blend of herbal extracts designed to dispel wind, dissipate cold, and resolve blood stasis, thereby reducing the frequency and severity of migraine attacks. It is being evaluated in a multicenter, randomized, double-blind, placebo-controlled trial (e.g., CTR20254404) to establish its efficacy and safety as a prophylactic therapy.

Brand names
Shufeng Zhitong Capsule
Other names
疏风止痛胶囊
02

Targets

IL-6 (Interleukin 6)CaV (Voltage-gated calcium channel protein complex)IL1B (Interleukin-1 beta)DRD2 (Dopamine D2 Receptor)MEK

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