Drug intelligence / Profile preview

Shugan Jieyu Xifeng Fang

Development stage
Preclinical
Administration
Oral
01

Overview

Shugan Jieyu Xifeng Fang (疏肝解郁熄风方) is a traditional Chinese medicine (TCM) herbal formula. The name translates to "Liver-Soothing, Depression-Relieving, Wind-Extinguishing Formula." It is designed according to TCM principles to soothe the liver, relieve emotional constraint or depression, and extinguish internal wind—a concept in TCM often associated with neurological symptoms such as tremors or convulsions. This formula typically combines herbs that regulate liver qi, resolve stagnation, calm the mind, and suppress wind. While specific ingredient lists for this exact named formula are not found in the provided sources, similar formulas often include Bupleurum root (Chai Hu), Cyperus rhizome (Xiang Fu), Uncaria stem (Gou Teng), Gastrodia rhizome (Tian Ma), among others[6][3]. These ingredients work synergistically to address mood disorders with neurological symptoms such as depression comorbid with epilepsy or movement disorders by harmonizing liver function and calming internal wind per TCM theory[6]. Clinical studies suggest that related formulas can improve depressive symptoms and reduce seizure frequency when used adjunctively with standard therapies[6].

Other names
疏肝解郁熄风方
02

Targets

ERKCREB (Cyclic AMP response element-binding protein)

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