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shugan lidan formula
- Development stage
- Preclinical
- Lead developer
- Second Hospital of Shandong University
- Administration
- Oral
01
Overview
Shugan Lidan Formula is a Traditional Chinese Medicine (TCM) herbal composition being investigated for its potential to prevent the recurrence of common bile duct stones (choledocholithiasis) following surgical or endoscopic removal. Developed and studied by researchers at The Second Hospital of Shandong University, the formula is designed to "soothe the liver and benefit the gallbladder," a TCM therapeutic principle aimed at improving bile secretion and flow (choleretic effect) and reducing biliary inflammation. By modulating the lithogenicity of bile and enhancing gallbladder motility, the formula seeks to address the underlying biliary stasis and metabolic imbalances that lead to stone formation.
- Other names
- Shugan Lidan DecoctionShugan Lidan Tang疏肝利胆方
02
Targets
ADIPOQ (Adiponectin)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)IL8 (C-X-C Motif Chemokine Ligand 8)IL-6 (Interleukin 6)PPARA (Peroxisome proliferator-activated receptor alpha)SREBP-1 / SREBF1 (SREBP-1)
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