Drug intelligence / Profile preview

shugan lidan formula

Development stage
Preclinical
Lead developer
Second Hospital of Shandong University
Administration
Oral
01

Overview

Shugan Lidan Formula is a Traditional Chinese Medicine (TCM) herbal composition being investigated for its potential to prevent the recurrence of common bile duct stones (choledocholithiasis) following surgical or endoscopic removal. Developed and studied by researchers at The Second Hospital of Shandong University, the formula is designed to "soothe the liver and benefit the gallbladder," a TCM therapeutic principle aimed at improving bile secretion and flow (choleretic effect) and reducing biliary inflammation. By modulating the lithogenicity of bile and enhancing gallbladder motility, the formula seeks to address the underlying biliary stasis and metabolic imbalances that lead to stone formation.

Other names
Shugan Lidan DecoctionShugan Lidan Tang疏肝利胆方
02

Targets

SREBP-1 / SREBF1 (SREBP-1)PPARA (Peroxisome proliferator-activated receptor alpha)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)IL8 (C-X-C Motif Chemokine Ligand 8)ADIPOQ (Adiponectin)IL-6 (Interleukin 6)

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