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Shuhe granules
- Development stage
- Unknown
- Lead developer
- The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Shuhe granules (舒合颗粒) is a Traditional Chinese Medicine (TCM) hospital preparation developed by the Second Affiliated Hospital of Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine). It is specifically formulated to treat rheumatoid arthritis (RA), particularly when accompanied by symptoms of insomnia, anxiety, or depression, which are categorized under the TCM syndrome of Liver-Qi stagnation and Spleen deficiency. The formula typically includes herbs such as *Paeonia lactiflora* (Bai Shao), *Glycyrrhiza uralensis* (Gan Cao), and *Ziziphus jujuba var. spinosa* (Suan Zao Ren). Its therapeutic mechanism involves the downregulation of pro-inflammatory cytokines (such as TNF and IL-6) to reduce joint inflammation and the modulation of the GABAergic system to improve sleep quality and emotional stability. As a hospital preparation, its use is primarily localized to the developing institution's clinical practice and is regulated under China's hospital-specific drug preparation standards.
- Brand names
- Shuhe granules
- Other names
- Shuhe Keli舒合颗粒
02
Targets
TNFA (Tumor necrosis factor alpha (soluble))GABA-B (Gamma-aminobutyric acid receptor type B)IL-6 (Interleukin 6)
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