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shuxinding sulfate
- Development stage
- Phase 2
- Lead developer
- Shanghai Institute of Materia Medica
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Shuxinding sulfate is an investigational small molecule anti-arrhythmic agent developed by the Shanghai Institute of Materia Medica (SIMM) of the Chinese Academy of Sciences. It is characterized as a multi-ion channel blocker that inhibits sodium, potassium, and calcium channels, thereby combining the pharmacological properties of Class I, III, and IV anti-arrhythmic drugs. The compound is primarily being developed for the treatment of ventricular arrhythmias, including frequent ventricular premature beats and non-sustained ventricular tachycardia. Clinical development has progressed to Phase 2 trials in China, where its safety and efficacy in stabilizing cardiac rhythm are being evaluated.
- Other names
- 舒心定Shuxinding
02
Targets
KCNQ1 (Potassium voltage-gated channel subfamily KQT member 1)NaV (Voltage-gated sodium channels)CaV (Voltage-gated calcium channel protein complex)
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