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Shuxuetong Injection
- Development stage
- Phase 4
- Lead developer
- Mudanjiang Youbo Pharmaceutical
- Modality
- Classical Binding Small Molecules → Small Molecules
- Administration
- Intravenous
01
Overview
Shuxuetong Injection is a multi-component traditional Chinese medicine injectable preparation derived from leech and earthworm source materials, reported as *Whitmania pigra* and *Pheretima aspergillum*, respectively. It is used in China for ischemic cerebrovascular disease, including acute ischemic stroke, and is being evaluated in a Dongzhimen Hospital patient registry as an adjunct to intravenous alteplase or tenecteplase. Its molecular pharmacology is not fully defined; preclinical ischemic-stroke research has associated the product with suppression of CD44/NLRP3/gasdermin D signaling and pyroptosis. ([clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06018181))
- Brand names
- Shuxuetong
- Other names
- ShuxuetongShuXueTong InjectionSXT疏血通注射液
02
Targets
BCL-2 (BCL-2 family)Misfolded SOD1VEGFA (Vascular endothelial growth factor A)XO (Xanthine Oxidoreductase)
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