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Shuyu Capsule
- Development stage
- Unknown
- Lead developer
- Qingdao Haichuang Center for Innovative Biomedical Research
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Shuyu Capsule (舒郁胶囊) is a Traditional Chinese Medicine (TCM) candidate developed by the Qingdao Haichuan Innovative Natural Medicine Research Center for the treatment of depression. It is specifically indicated for patients presenting with the "liver qi stagnation" (肝气郁结) syndrome, a common diagnostic pattern in TCM associated with mood disorders. The drug is formulated as an oral capsule and has been evaluated in Phase IIa clinical trials (such as CTR20150008) to assess its efficacy and safety using the Hamilton Depression Rating Scale (HAMD) as a primary endpoint. As a natural medicine product, it likely functions through the synergistic effects of multiple botanical constituents targeting various pathways in the central nervous system and the neuroendocrine system.
- Other names
- 舒郁胶囊
02
Targets
HTR3B (5-hydroxytryptamine receptor 3B)MOR (Mu opioid receptor)HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))CACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C)HTR3A (5-hydroxytryptamine receptor 3A)GABRD (GABA-A receptor subunit delta)
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