Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
si-CRISP3
- Development stage
- Preclinical
- Modality
- Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01
Overview
si-CRISP3 is a small interfering RNA (siRNA) designed to silence the expression of the Cysteine-Rich Secretory Protein 3 (CRISP3) gene. In the context of prostate cancer research, CRISP3 has been identified as a critical factor that promotes tumor cell proliferation and metastasis by inducing the epithelial-to-mesenchymal transition (EMT). By targeting CRISP3 mRNA for degradation, si-CRISP3 inhibits these oncogenic processes, making it a valuable tool for studying the molecular mechanisms of bone metastatic prostate cancer and a potential candidate for RNA-based therapeutic strategies.
- Other names
- CRISP3 siRNACRISP-3 siRNACRISP 3 siRNAsmall interfering RNA targeting CRISP3
Beyond the preview
Go deeper on si-CRISP3.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on si-CRISP3.