Sichuan Univ. GPR68 compound 18l

Sichuan Univ. GPR68 compound 18l: sourced facts only. name: "Structure-activity relationship (SAR) of these compounds was analyzed, which led to the identification of a potent GPR68 antagonist (18l) with an IC50 value of 0.081 ± 0.006 μM." [PMID:41610652]; target: "Structure-activity relationship (SAR) of these compounds was analyzed, which led to the identification of a potent GPR68 antagonist (18l) with an IC50 value of 0.081 ± 0.006 μM." [PMID:41610652]; developer: "Key Laboratory of Drug Targeting and Drug Delivery System of Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu, Sichuan, 610041, China." [PMID:41610652]; stage: "In a dextran sulfate sodium (DSS)-induced mouse model of IBD, 18l effectively alleviated disease symptoms." [PMID:41610652]