Sichuan Univ. MAGL compound 55

Sichuan Univ. MAGL compound 55: sourced facts only. name: "Herein, we reported the design and synthesis of a new series of piperazine derivatives possessing a naphthyl group (7-64), leading to the identification of 55, which displayed high MAGL inhibition with a pIC50 value of 8.0 ± 0.1." [PMID:40403414]; target: "Herein, we reported the design and synthesis of a new series of piperazine derivatives possessing a naphthyl group (7-64), leading to the identification of 55, which displayed high MAGL inhibition with a pIC50 value of 8.0 ± 0.1." [PMID:40403414]; developer: "Department of Pulmonary and Critical Care Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu 610065, China; Targeted Tracer Research and Development Laboratory, Institute of Respiratory Health, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610065, China; Precision Medicine Center, Precision Medicine Key Laboratory of Sichuan Province, West China Hospital, Sichuan University, Chengdu 610065, China." [PMID:40403414]; stage: "Moreover, 55 showed appreciable antiproliferative activity and apoptosis induction, as well as the ability to reduce cell migration in cancer cells such as HT-29." [PMID:40403414]