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**SII Inactivated Salk Polio Vaccine** is Serum Institute of India's adsorbed, reduced-dose trivalent inactivated poliovirus vaccine for prevention of poliomyelitis caused by poliovirus types 1, 2, and 3. Each 0.5 mL dose contains inactivated poliovirus type 1 Mahoney strain, type 2 MEF-1 strain, and type 3 Saukett strain, produced in Vero cells and adsorbed to aluminum hydroxide. It induces neutralizing humoral immunity against the three poliovirus serotypes and was evaluated in a completed randomized Phase III infant study assessing immunogenicity, safety, and lot-to-lot consistency. ([cdsco.gov.in](https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadCTApprovals/8_SERUM_IPV.pdf))
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