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SII Yellow Fever Vaccine
- Development stage
- Unknown
- Lead developer
- Serum Institute of India
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Subcutaneous, Intramuscular
01
Overview
The SII Yellow Fever Vaccine is a live attenuated viral vaccine developed by the Serum Institute of India for the prevention of yellow fever. It contains the 17D-213 strain of the yellow fever virus, which is a derivative of the 17D-204 strain used in many currently licensed yellow fever vaccines. The vaccine is propagated in specific pathogen-free chick embryos and is designed to induce protective immunity against the yellow fever virus through a single dose. It is currently being evaluated in Phase III clinical trials, specifically targeting healthy infants aged 9 to 12 months in sub-Saharan Africa, to compare its safety and immunogenicity against the reference vaccine, STAMARIL. The development of this vaccine aims to address the global supply shortage of yellow fever vaccines.
- Other names
- Yellow fever vaccine (Serum Institute of India)SIIPL Yellow Fever Vaccine17D-213 strain vaccine
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