sijunzi decoction + prunella vulgaris

Sijunzi decoction + Prunella vulgaris is a combination of two well-established traditional Chinese medicine (TCM) products: Sijunzi Decoction (SJZD), a classical TCM formula primarily used for the management of spleen deficiency and related gastrointestinal disorders, and Prunella vulgaris, a medicinal herb with claimed activities in immunomodulation, anti-inflammatory, anticancer, and antiviral effects. - **Sijunzi Decoction** comprises four core herbs: Panax ginseng (or Codonopsis radix), Atractylodes macrocephala, Wolfiporia cocos, and Glycyrrhiza uralensis. The principal actions are replenishing Qi, strengthening the spleen and stomach, tonifying deficiency, and promoting gastrointestinal function. Mechanisms include improving mucosal barrier function and regulating intestinal immunity[2][4][6][8][10]. - **Prunella vulgaris** (self-heal, Xia-Ku-Cao) contributes additional pharmacological activities including anti-inflammatory, antiviral, anticancer, and immune-modulating properties, due to its content of polysaccharides, triterpenes, flavonoids, and phenolic acids. Traditionally, it is used to clear liver fire, disperse swelling, and has applications in sore throat, goiter, and breast disorders[1][5][7][9]. Together, the combination is used in TCM to treat broader indications where strengthening the spleen, supporting gastrointestinal health, and providing anti-inflammatory or tumor-suppressive actions are desired.

Other names

SJZD + Prunella vulgaris四君子汤 + 夏枯草