silicon-based hydrogen-generating agent

Silicon-based hydrogen-generating agent is an investigational, orally administered antioxidant agent composed of nano-sized silicon particles. Developed by researchers at Osaka University in collaboration with Nobelpharma and Osaka Titanium Technologies, the agent is designed to continuously generate large amounts of molecular hydrogen in the alkaline environment of the intestinal tract (pH 7-9) upon reaction with water. The generated molecular hydrogen acts as a selective scavenger of harmful reactive oxygen species (ROS), particularly hydroxyl radicals, without disrupting physiologically beneficial ROS. Preclinical studies have demonstrated its therapeutic potential in various oxidative stress-related conditions, including ulcerative colitis, chronic kidney disease, Parkinson's disease, ischemia-reperfusion injury, and antibody-mediated rejection after kidney transplantation.

Other names

Si-based agenthydrogen-generating silicon-based agentnano-sized silicon particlessilicon agentsilicon-based agent