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**Silicone gel with superoxidized water** is an investigational topical silicone-based gel formulation developed by Fundación Nacional para la Enseñanza y la Investigación de la Dermatología for hypertrophic scars and keloids. The product combines silicone, intended to form a protective occlusive scar-treatment layer, with superoxidized water. Its proposed therapeutic activity is local scar modulation through hydration and occlusion of scar tissue, with superoxidized water potentially contributing local antimicrobial and anti-inflammatory effects. It has been described in provided trial metadata as being compared with topical pirfenidone gel in an observer-blind randomized pilot study.
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