Siliphos

Siliphos is a patented dietary supplement and botanical extract that combines silybin (the most active flavonoid from milk thistle, Silybum marianum) with phospholipids (phosphatidylcholine) to form a highly bioavailable complex. This formulation significantly enhances the absorption and bioavailability of silybin compared to standard milk thistle or silymarin extracts. The primary mechanism of action is antioxidant activity—neutralizing free radicals and protecting liver cells from oxidative stress—and supporting detoxification processes in the liver. Siliphos also stimulates protein synthesis in hepatocytes and helps maintain normal levels of glutathione, contributing to overall liver health. It is primarily used for liver support but has also been marketed as a natural alternative to retinoids for skin health due to its effects on collagen production and wrinkle reduction[1][2][3][4][5][6][8][9][10].

Brand names

Siliphos

Other names

silybin-phytosomesilybin phytosomemilk thistle phytosomeSilybum marianum extract/phospholipid complex