Drug intelligence / Profile preview

silver + EmoLED

Development stage
Unknown
Lead developer
Emoled
Modality
Small Molecules
Administration
Topical
01

Overview

EmoLED is a Class IIa medical device developed by Emoled Srl that utilizes blue light photobiomodulation (wavelength 400-430 nm) to accelerate the healing of chronic wounds, including stage II and III pressure ulcers. The 'silver-EmoLED' protocol refers to a combination therapy where the EmoLED device is used as an adjuvant to standard wound care that includes topical silver agents, such as ionic silver spray powder or hyaluronic acid sodium salt with metallic silver. The blue light therapy works by interacting with endogenous photoreceptors like mitochondrial cytochrome c oxidase to modulate inflammation and stimulate tissue repair. The silver component provides broad-spectrum antimicrobial activity to manage the wound bioburden, preventing or treating infection in the ulcerated area. This combination has been evaluated in clinical studies like the RISE_UP trial to verify its effectiveness in supporting the reparative process of decubitus lesions.

Brand names
EmoLED
Other names
blue light photobiomodulation + silversilver-EmoLED therapyionic silver spray + EmoLED
02

Targets

COX7C (Cytochrome c oxidase subunit 7C, mitochondrial)Neuraminidase

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