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silver nanoparticles from Eclipta prostrata

Development stage
Preclinical
Lead developer
Sri Venkateswara College
Modality
Nanoparticles → Drug Delivery Systems
Administration
Oral
01

Overview

Silver nanoparticles from Eclipta prostrata (SEP) are green-synthesized metallic nanoparticles prepared using the aqueous leaf extract of the medicinal plant *Eclipta prostrata* (Bhringaraj) as a reducing and stabilizing agent. These biogenic nanoparticles are designed to enhance the bioavailability and central nervous system penetration of neuroprotective phytochemicals. In preclinical murine models of Parkinson's disease, SEP has demonstrated neuroprotective, antiparkinsonian, and antioxidant effects, significantly ameliorating motor deficits, tardive dyskinesia, and oxidative stress by replenishing antioxidant defenses and reducing lipid peroxidation.

Other names
Eclipta prostrata-derived silver nanoparticlesgreen-synthesized silver nanoparticles from Eclipta prostratasilver nanoparticles synthesized from Eclipta prostrata
02

Targets

DNAATP SynthaseRibosome

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