Drug intelligence / Profile preview

silver polyacrylate

Development stage
Unknown
Lead developer
Gemo-Pro
Modality
Implantable Hydrogels → Hydrogel Systems → Drug Delivery Systems, Small Molecules, Non-biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Injectable Hydrogels → Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

Hemoblock is a topical hemostatic agent composed of a silver salt of polyacrylic acid (silver polyacrylate). It is primarily indicated for the management of capillary and parenchymal hemorrhages during surgical interventions, trauma, and dental procedures. The drug's mechanism of action involves the rapid formation of a stable protein-polyacrylate complex upon contact with blood proteins, particularly albumin. This process results in the creation of a mechanical barrier or clot that seals damaged vessels without relying on the patient's endogenous coagulation factors, making it effective even in the presence of coagulopathies or anticoagulant therapy. Furthermore, the presence of silver ions imparts broad-spectrum antimicrobial properties to the solution, which helps prevent secondary wound infections. Hemoblock is typically applied topically as a solution or via impregnated dressings and is characterized by its minimal tissue reaction and lack of systemic absorption.

Brand names
HemoblockGemo-Block
Other names
Silver salt of polyacrylic acid

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