Drug intelligence / Profile preview

silybin + vitamin E + phospholipids

Development stage
Phase 3
Lead developer
IBI Lorenzini
Modality
Small Molecules
Administration
Oral
01

Overview

A complex formulation that combines silybin (the main component of silymarin, a natural flavonoid) with vitamin E and phospholipids to improve its bioavailability and antioxidant activity. This complex has been studied for its effects on liver conditions, particularly non-alcoholic fatty liver disease (NAFLD) and HCV-related chronic hepatitis. It shows significant improvements in liver steatosis, enzyme levels, insulin resistance, and markers of liver fibrosis.

Brand names
RealsilRA
Other names
silybin-vitamin E-phospholipid complexsilybin phytosome complexSilPho
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))

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