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SIM05
- Development stage
- Unknown
- Lead developer
- Chinese University of Hong Kong Faculty of Medicine
- Modality
- Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
SIM05 is a blend of three food-grade probiotic strains and three prebiotics, designed as a dietary supplement to modulate gut microbiota. The formulation includes *Bifidobacterium* and *Lactobacillus* species, which are commonly used probiotic cultures in food products. It is being investigated for its potential to alleviate symptoms of atopic eczema in adults by altering the gut microbiome. A pilot clinical study is underway to assess its efficacy and safety for this indication[1][3].
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