Drug intelligence / Profile preview

Simvacard

Development stage
Unknown
Lead developer
Zentiva
Modality
Small Molecules
Administration
Oral
01

Overview

Simvacard is a branded pharmaceutical formulation of simvastatin, a small molecule HMG-CoA reductase inhibitor (statin). Developed and manufactured by Zentiva, it is primarily used to treat lipid disorders such as primary hypercholesterolemia and mixed dyslipidemia. By inhibiting HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol synthesis, it reduces LDL cholesterol and triglyceride levels while increasing HDL cholesterol. It is also indicated for the secondary prevention of cardiovascular events, including myocardial infarction and stroke, in patients with coronary heart disease or high cardiovascular risk. The medication is typically administered orally in tablet form.

Brand names
Simvacard
Other names
simvastatin
02

Targets

HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)

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