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Drug intelligence / Profile preview
Sinarest Plus
- Development stage
- Unknown
- Lead developer
- Centaur Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Sinarest Plus is a fixed-dose combination medication developed by Centaur Pharmaceuticals for the treatment of symptoms associated with the common cold, flu, allergic rhinitis, and upper respiratory tract infections. It is available in multiple formulations, including a pediatric suspension and an adult tablet. The pediatric suspension formulation typically contains paracetamol (acetaminophen) as an analgesic and antipyretic, phenylephrine hydrochloride as a nasal decongestant, chlorpheniramine maleate as an antihistamine, sodium citrate as a mucolytic/alkalinizing agent, and menthol for its cooling effect. The adult tablet formulation contains paracetamol, phenylephrine, chlorpheniramine, and caffeine to enhance the analgesic effect and reduce drowsiness. Together, these components work synergistically to relieve fever, body aches, nasal congestion, runny nose, sneezing, and cough.
- Brand names
- Sinarest PlusSinarest Plus SuspensionSinarest Plus Tablet
- Other names
- Sinarest Plus range
02
Targets
ADORA1 (Adenosine receptor A1 subtype)ADORA2A (Adenosine A₂A Receptor)ADRA1A (α1A)ADRA1B (α1B)ADRA1D (α1D)HRH1 (Histamine H1 Receptor)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)TRPM8 (Transient receptor potential cation channel subfamily M member 8)
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