Drug intelligence / Profile preview

SIR-T PSCA

Development stage
Preclinical
Lead developer
Angeles Therapeutics
Modality
Cell Therapies
Administration
Intravenous
01

Overview

SIR-T PSCA is an engineered cell therapy being developed by Angeles Therapeutics for the treatment of cancers expressing Prostate Stem Cell Antigen (PSCA). The therapy utilizes the company's proprietary Synthetic Immune Receptor (SIR-T) platform, which is designed to mimic natural T-cell signaling to enhance the recognition and destruction of tumor cells. By targeting PSCA, a cell surface protein frequently overexpressed in prostate, pancreatic, and bladder cancers, SIR-T PSCA aims to provide a potent and selective immune response against these malignancies. It is currently in the late discovery stage of development.

02

Targets

PSCA (Prostate stem cell antigen)

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