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Siriraj Mite Allergen Vaccine
- Development stage
- Unknown
- Lead developer
- Faculty of Medicine Siriraj Hospital Mahidol University
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Subcutaneous
01
Overview
Siriraj Mite Allergen Vaccine (SMAV) is a locally standardized allergen immunotherapy (AIT) product developed at Siriraj Hospital, Mahidol University, Thailand. It consists of a biological extract of *Dermatophagoides pteronyssinus* (house dust mite) allergens. SMAV is designed for subcutaneous administration to treat perennial allergic rhinitis in patients sensitized to house dust mites. The vaccine works by inducing immunotolerance through the modulation of the immune system, specifically targeting the allergic response to *D. pteronyssinus* allergens to reduce symptoms and medication requirements. It represents a locally developed biologic designed specifically for the Thai population.
- Other names
- Mite Allergen VaccineDermatophagoides pteronyssinus allergen extract
02
Targets
HDM-specific IgE (House dust mite-specific immunoglobulin E)
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