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siRNA-HSPA4
- Development stage
- Preclinical
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
01
Overview
siRNA-HSPA4 is an **experimental RNA interference therapeutic concept** consisting of a small interfering RNA designed to silence **HSPA4** expression. Based on the available literature, HSPA4 knockdown has been studied in melanoma cell models, where siRNA-mediated suppression of HSPA4 reduced proliferation of A-375 melanoma cells, supporting HSPA4 as a potential oncology target. However, the available evidence appears to be limited to preclinical research use, and no clearly identifiable named clinical-stage drug product, sponsoring developer, or commercial program for a specific therapeutic agent called siRNA-HSPA4 could be confirmed from the provided context.
- Other names
- HSPA4 siRNAHSPA-4 siRNAHSPA 4 siRNAsmall interfering RNA targeting HSPA4
02
Targets
HSPA4 (Heat shock 70 kDa protein 4)
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