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siSRF797
- Development stage
- Preclinical
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Intravenous
01
Overview
siSRF797 is a small interfering RNA (siRNA) drug candidate targeting serum response factor (SRF) mRNA. Its mechanism involves the selective silencing of the SRF gene by promoting the degradation of its messenger RNA, thereby reducing SRF protein levels. SRF is a transcription factor implicated in fibrosis and various pathologies; thus, siSRF797 is primarily being researched for disorders related to fibrosis and pathological tissue remodeling. The specific developer and manufacturing companies have not been identified in publicly available sources. siSRF797 is under preclinical or early clinical investigation; no marketing approval has been reported.
- Other names
- siSRF797siSRF-797siSRF 797
02
Targets
SRF (Serum response factor)
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