Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
siVEGF
- Development stage
- Preclinical
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Intravenous, Intratumoral, Transdermal, Intravitreal
01
Overview
siVEGF is a small interfering RNA (siRNA) designed to inhibit the expression of Vascular Endothelial Growth Factor (VEGF) at the genetic level through RNA interference. VEGF is a key protein involved in angiogenesis, a process crucial for tumor growth, ocular neovascular diseases, and other conditions. By silencing VEGF gene expression, siVEGF aims to block the biological effects of VEGF, thereby inhibiting angiogenesis, tumor proliferation, and metastasis. It is often delivered using various nanocarrier systems to improve stability, targeting, and cellular uptake, and is being investigated in combination therapies with chemotherapeutics or photodynamic therapy to enhance anti-tumor efficacy and overcome resistance.
- Other names
- small interfering RNA for VEGFVEGF siRNA
02
Targets
Beyond the preview
Go deeper on siVEGF.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on siVEGF.