SK-PC-B70M

SK-PC-B70M is an oleanolic-glycoside saponin-enriched fraction derived from the root of Pulsatilla koreana. Its active ingredient includes hederacolchiside-E, which has demonstrated neuroprotective and cognition-enhancing effects in preclinical studies. The compound has shown efficacy in improving memory consolidation and spatial working memory impairments induced by scopolamine in animal models, as well as reducing amyloid-beta (Aβ) levels and plaque deposition in transgenic mouse models of Alzheimer's disease. Additionally, it exhibits antioxidant properties by reducing lipid peroxidation by-products such as malondialdehyde (MDA) and 4-hydroxy-2-nonenal (HNE), suggesting a role in attenuating neurodegenerative pathology. Clinical development was primarily focused on Alzheimer's disease[1][2][5][6].