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Drug intelligence / Profile preview
Skunk Haze
- Development stage
- Phase 3
- Lead developer
- CBD Crew
- Modality
- Small Molecules
- Administration
- Inhalation, Oral
01
Overview
Skunk Haze is a hybrid cannabis cultivar, traditionally a cross between Skunk #1 and Haze genetics. In the medical cannabis industry, it is most notably recognized as **CBD Skunk Haze**, a stabilized 1:1 THC:CBD variety developed by the **CBD Crew** (a collaboration between Mr. Nice Seeds and Resin Seeds). This balanced cannabinoid profile is intended to provide therapeutic relief for symptoms such as chronic pain, inflammation, and muscle spasticity while reducing the risk of THC-induced anxiety or paranoia. The strain's primary active components, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), interact with the human endocannabinoid system and various non-cannabinoid receptors. THC acts as a partial agonist at the CB1 and CB2 receptors, while CBD functions as a negative allosteric modulator of CB1 and an agonist at the 5-HT1A serotonin receptor, contributing to its analgesic and anxiolytic properties.
- Brand names
- CBD Skunk Haze
- Other names
- Skunk x Haze
02
Targets
HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))CNR1 (Cannabinoid receptor 1)
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