Drug intelligence / Profile preview

SKY01

Development stage
Preclinical
Lead developer
SEEKYO Therapeutics
Modality
Lipid-mediated Delivery → Gene Addition/Replacement → Gene Therapies, Viral Vectors → Gene Addition/Replacement → Gene Therapies, Physical Methods → Gene Addition/Replacement → Gene Therapies
Administration
Intravenous
01

Overview

SKY01 is a preclinical chemotherapy drug candidate developed by Seekyo for the treatment of solid tumors. It utilizes therapeutic vectors that are specifically activated by enzymes within the tumor microenvironment, offering a potential alternative to Antibody-Drug Conjugates (ADCs). The drug is currently undergoing toxicology and pharmacokinetics studies to prepare for future clinical trials.

02

Targets

GUSB (Beta-glucuronidase)

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