Drug intelligence / Profile preview

SLP07

Development stage
Preclinical
Lead developer
GenieBiome
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

SLP07 is an investigational synbiotic formulation developed for the treatment of metabolic dysfunction-associated fatty liver disease (MAFLD), formerly known as non-alcoholic fatty liver disease (NAFLD). The product consists of a proprietary blend of naturally occurring, food-grade probiotic strains from the *Bifidobacterium* and *Lactobacillus* genera, combined with omega-3 polyunsaturated fatty acids and vitamin E. SLP07 is designed to modulate the gut microbiota and the gut-liver axis, potentially reducing liver injury by decreasing gut-derived lipopolysaccharides (LPS) and pro-inflammatory cytokines such as TNF-α. The inclusion of vitamin E and omega-3 fatty acids provides additional antioxidant and lipid-lowering effects to improve liver function and reduce hepatic steatosis.

Other names
SLP07 synbioticSLP-07 synbioticSLP 07 synbiotic
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))

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