Drug intelligence / Profile preview

SLS-008

Development stage
Preclinical
Lead developer
Seelos Therapeutics
Modality
Small Molecules
Administration
Oral
01

Overview

SLS-008 is a small molecule, orally bioavailable antagonist of the prostaglandin D2 (PGD2) receptor, specifically targeting the chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2). It is developed for the treatment of atopic dermatitis, pediatric esophagitis, and asthma. Initially developed by Ligand Pharmaceuticals, it is currently in the preclinical phase of development.

Other names
SLS008SLS-008SLS 008
02

Targets

PTGDR2 (Prostaglandin D2 receptor 2)PTGDR (Prostanoid DP1 receptor)

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