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SLV-154 is an investigational intravenous antineoplastic agent developed by Solve Therapeutics for the treatment of metastatic solid tumors and a range of advanced cancers. It is currently in early clinical development, with a Phase 1 dose-escalation study underway to evaluate its safety, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary efficacy in patients with metastatic solid tumors. The precise mechanism of action for SLV-154 has not been disclosed as of the latest updates. Indications under investigation include advanced breast cancer (including HER2 positive), cervical cancer, endometrial cancer, head and neck cancer, non-small cell lung cancer, ovarian cancer, sarcoma, small cell lung cancer, squamous cell carcinoma, urogenital cancers as well as other solid tumors.
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