SM70EE

SM70EE is a standardized **70% ethanol extract of Spirulina maxima**, a marine microalga. It is under investigation for its potential cognitive benefits, particularly for improving memory in older adults with **mild cognitive impairment (MCI)**. SM70EE demonstrates antioxidant effects, is thought to mitigate memory loss possibly by reducing hippocampal beta-amyloid (Aβ1-42) accumulation, inhibiting amyloid precursor protein processing, and modulating synaptic and neurotrophic pathways. Clinical trials have reported **statistically significant improvements in visual learning, visual working memory, and vocabulary** in MCI patients over 12 weeks, with an excellent safety profile. Preclinical studies suggest mechanisms involving antioxidative action, acetylcholinesterase inhibition, enhanced brain-derived neurotrophic factor (BDNF), and modulation of neuroinflammation.

Other names

Spirulina maxima 70% ethanol extract