small interfering RNA targeting DNMT3B

A **small interfering RNA targeting DNMT3B** is an experimental RNA interference therapeutic concept designed to reduce expression of **DNA methyltransferase 3 beta**, an epigenetic writer implicated in tumor cell proliferation and adverse prognosis in some cancers. In the provided source context, DNMT3B inhibition was used as a research tool in esophageal cancer models and was associated with disruption of S phase progression and reduced cancer cell proliferation. No unique development code, sponsor, branded product, clinical-stage asset identity, formulation, or company-specific program could be confidently established from the supplied evidence, so this should be treated as a target-directed investigational siRNA construct rather than a clearly identified named drug product.

Other names

siRNA targeting DNMT3BDNMT3B siRNADNMT-3B siRNADNMT 3B siRNAsmall interfering RNA targeting DNA methyltransferase 3 beta