Drug intelligence / Profile preview

small intestinal release peppermint oil

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

Small intestinal release peppermint oil is an enteric-coated formulation of peppermint oil designed to release its contents in the small intestine. The main active constituent is L-menthol, which exerts a dose-related antispasmodic effect on gastrointestinal smooth muscle by inhibiting calcium influx into smooth muscle cells[7]. This formulation is primarily used to treat symptoms of irritable bowel syndrome (IBS), including abdominal pain, bloating, gas, and diarrhea[2][4]. The enteric coating prevents premature release in the stomach, which can cause heartburn and indigestion, ensuring the active ingredients reach the small intestine where they can act directly on intestinal smooth muscle[4].

02

Targets

CaV3 (Caveolin-3)SLC5A1 (Sodium Glucose Cotransporter 1)CACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C)

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